As a new leadership style , humble leadership has attracted increasing attention to researchers .Yet at this initial stage , the relevant studies on humble leadership are far from being sufficiently researched .Though some scholars have discussed some outcomes of humble leadership , almost none of them has ever investigated the relationship between humble leadership and em -ployee creativity directly .To fill the gap, this study aims to address following two research questions:①Can humble leadership behaviors improve the employee creativity?If so, and how?②How dose employee′s personality traits affect the relationship be-tween humble leadership behavior and employee creativity?This study, first of all, explored the mental mechanism between hum-ble leadership behavior and employee creativity in respects to psychological safety and self -efficacy .Then it discussed the effec-tiveness of humble leadership from the perspective of the discrimination of employees ′regulatory focus . In total, 340 employees and their 84 supervisors from a large private manufacturing enterprise located in Hangzhou were sampled . To avoid the common method variance problem , two sources of survey were administrated .Employees were asked to provide rat-ings of humble leadership behavior , self-reported psychological safety , self-efficacy and regulatory focus .The corresponding su-pervisors were asked to provide ratings of employee creativity .The final matched sample was 326, resulting valid response rates 95.882%.Among the major measures, the 9-item humble leadership behavior scale was adopted from Owens et al′(2013) study;Regulatory focus was measured via 7 items that were used by Zhou et al ( 2012 ) while the perception of psychological safety was measured according to the scales developed by Edmondson (1999) and Siemsen et al(2008).The 8-item self-efficacy scale was adapted from Chen et al ( 2001 ) and the 4-item employee creativity scale was adapted from Farmer et al ( 2003 ) . Cronbach′s alpha values for these measures ranged from 0.715 to 0.883, indicating acceptable measurement reliabilities . Structural equation modeling and hierarchical regression modeling were employed to analyze the data .Results show that humble leadership behavior is positively related to employee creativity , which is fully mediated by psychological safety and self-efficacy. Employees′prevention focus positively moderates the positive correlation between humble leadership behavior and psychological safety.Employees-promotion focus positively moderates the positive correlation between humble leadership behavior and self -effi-cacy.Therefore, this study provides a new way of thinking for leaders to use humble leadership behaviors to promote the employ -ee creativity instead of adopting the traditional top-down leadership style .