学术论文

      Clinical Application of Vibration Controlled Transient Elastography in Patients with Chronic Hepatitis B

      Abstract:
      Evaluation of the extent and progression of liver fibrosis and cirrhosis is of critical importance in the management and prognosis of patients with chronic hepatitis B.Due to the limitation of liver biopsy,non-invasive methods,especially liver stiffness measurement (LSM) by vibration controlled transient elastography,have been developed and widely applied for liver fibrosis assessment.LSM aims to reduce,but not to substitute,the need for liver biopsy for fibrosis/cirrhosis diagnosis.While LSM may have potential utility in monitoring treatment response,its applications in prediction of liver complications in terms of portal hypertension and esophageal varices,as well as disease prognosis,have been gradually validated.Here,we review the latest clinical applications of LSM in patients with chronic hepatitis B.
      Author: Xie-Er Liang Yong-Peng Chen
      作者单位: State Key Laboratory of Organ Failure Research, Guangdong Provincial Key Laboratory of Viral Hepatitis Research, Department of Infectious Diseases and Hepatology Unit, Nanfang Hospital, Southern Medical University, Guangzhou, China
      年,卷(期): 2017, 5(4)
      在线出版日期: 2017年12月18日
      基金项目: This study was funded by the National Science and Technology Major Project,the Dean's Fund of Nanfang Hospital