学术论文

      高龄产妇合并梅毒患者胎儿宫内感染的彩超诊断分析

      Color ultrasound diagnosis of fetal intrauterine infection in pregnant women with syphilis

      摘要:
      目的:探讨彩超诊断在高龄产妇合并梅毒患者胎儿宫内感染的诊断效果.方法:随机选取我院在2015年5月至2016年7月期间,确诊并接受治疗的50例发生宫内感染高龄合并梅毒产妇作为治疗组,选取同期在本院分娩的正常产妇50例作为对照组,对两组产妇产前的彩超诊断结果进行对比分析,根据两组的差异性总结可以作为早期胎儿宫内感染的判断指标;以分娩过程中所知宫内是否感染作为金标准,以ROC曲线分析产前超声对于梅毒高龄产妇是否合并宫内感染的诊断价值,并计算诊断效能指标:符合率、特异度、灵敏度、误诊率、漏诊率;分析产前超声诊断与金标准间的一致性.结果:通过对两组的彩超检查结果进行对比总结发现,两组产妇在以下指标上存在明显的差异:胎囊不规则、胎心异常、胎动异常、胎盘水肿,两组比较差异具有统计学意义(P<0.01);对两组产妇在医学探究各时间段所做的梅毒检测结果进行对比,治疗组感染比例低于对照组,差异具有统计学意义(P<0.05).结论:通过产前彩超诊断可以为医生提供更加直观详细的临床数据,便于对高龄产妇进行全面的诊断与评估并制定针对性的方案,提高分娩的安全系数,降低新生儿患有梅毒的几率.
      Abstract:
      Objectives:To explore the diagnosis effect of color ultrasound on fetal intrauterine infection in pregnant women with syphilis.Methods:50 intrauterine syphilis infected pregnant women at advanced age in our hospital from May 2015 to July 2016 were randomly selected as treatment group.50 health pregnant women were selected as control group.Diagnose results of color ultrasound in two groups were analyzed,and the index of early fetal intrauterine infection was summarized.Results:By comparing results of color ultrasound in two groups,it was found that there were significant differences in the following indicators:irregular embryo sac,abnormal fetal heart rate,abnormal quickened,placenta edema,and the differences were statistically significant (P <0.01).Comparing the test results of syphilis infection in two groups during pregnancy,the infection rate of treatment group was lower than that of control group,and the difference had statistical significance (P < 0.05).Conclusion:The diagnosis of color ultrasound can provide more intuitive detailed clinical data for the doctor,help to conduct a comprehensive diagnosis,evaluate and formulate specific methods,which can improve the safety of childbirth and reduce the incidence of neonatal infected with syphilis.
      作者: 苑丽双 [1] 聂军红 [2] 栗河舟 [3] 申爱荣 [4]
      Author: YUAN Lishuang [1] NIE Junhong [2] LI Hezhou [3] SHEN Airong [4]
      作者单位: 衡水市妇幼保健院儿科,河北衡水,053000 衡水市第二人民医院儿科,河北衡水,053000 郑州大学第三附属医院超声科,郑州,450052 郑州大学第三附属医院妇产科,郑州,450052
      刊 名: 中国性科学 ISTIC
      年,卷(期): 2017, 26(11)
      分类号: R759.1
      在线出版日期: 2017年12月22日
      基金项目: 河南省医学科技攻关计划项目