According to the relevant theory of statistics, good clinical research requires large sample sizes to support good power of test, and single-center research is often difficult to meet this requirement. Therefore, multi-center design has become the trend of contemporary clinical research. In the multi-center research, each center produces a large amount of data during the experiment. Good data management is one of the key links for successful multi-center research. REDCap, a web-based electronic data capture electronic, facilitates multi-center research data management. This article mainly introduces how to use REDCap to implement multi-center research data management.